Details of the Drug Formulations

General Information of Drug (ID: DMJTEMW)

• Drug Name: Lubiprostone Drug Info
• Synonyms: Amitiza; Lubiprostone [USAN]; RU 0211; RU0211; SPI 0211; SPI0211; AMITIZA (TN); RU-0211; SPI-0211; Amitiza, RU-0211, SPI-0211, Lubiprostone; (-)-7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta (b)pyran-5-yl)heptanoic acid; (-)-7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta(b)pyran-5-yl)heptanoic acid; 7-((1R,4R,6R,9R)-4-(1,1-difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo(4.3.0)non-9-yl)heptanoic acid; 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid

Indication

Disease Entry	ICD 11	Status	REF
Chronic idiopathic constipation	DC32	Approved	[1]

• Therapeutic Class: Anticonstipation Agents
• Cross-matching ID:
  PubChem CID: 157920
  CAS Number: 333963-40-9
  TTD ID: D00CTS
  ACDINA ID: D00380

Full List of Drug Formulations Containing This Drug

Lubiprostone 0.024 mg capsule

Company	Formulation ID	FDA Description
Takeda Pharmaceuticals America	F12691	D&c yellow no. 10; Fd&c red no. 40; Sorbitol; Water; Medium-chain triglycerides; Gelatin, unspecified
Carilion Materials Management; Physicians Total Care	F12692	D&c yellow no. 10; Fd&c red no. 40; Sorbitol; Water; Medium-chain triglycerides; Gelatin

Lubiprostone 0.008 mg capsule

Company	Formulation ID	FDA Description
Takeda Pharmaceuticals America	F12689	Sorbitol; Ferric oxide red; Titanium dioxide; Water; Medium-chain triglycerides; Gelatin, unspecified
Physicians Total Care; Stat Rx USA	F12690	Sorbitol; Ferric oxide red; Titanium dioxide; Water; Medium-chain triglycerides; Gelatin

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4242).