Details of the Drug Formulations

General Information of Drug (ID: DMJV2EK)

• Drug Name: Dasatinib Drug Info
• Synonyms: Sprycel (TN); BMS 354825; BMS-354825; BMS-354825, Sprycel, BMS354825, Dasatinib; BMS354825; Dasatinib (USAN); Dasatinib [USAN]; Dasatinib anhydrous; Dasatinib, BMS 354825; Dasatinibum; Sprycel; Spyrcel

Indication

Disease Entry	ICD 11	Status	REF
Blast phase chronic myelogenous leukemia, BCR-ABL1 positive		Approved	[1]
Brain disease	8C70-8E61	Approved	[1]
Central nervous system disease	8A04-8D87	Approved	[1]
Chronic myelogenous leukaemia	2A20.0	Approved	[2]
Chronic myeloid leukaemia	2A20	Approved	[3]
Glioblastoma	2A00	Approved	[1]
Leukemia		Approved	[1]
Lung cancer	2C25.0	Approved	[1]
Non-small-cell lung cancer	2C25.Y	Approved	[1]
Plasma cell myeloma	2A83.1	Approved	[1]
Multiple myeloma	2A83	Phase 2	[2]
Middle East Respiratory Syndrome (MERS)	1D64	Investigative	[4]
Severe acute respiratory syndrome (SARS)	1D65	Investigative	[4]

• Therapeutic Class: Anticancer Agents
• Cross-matching ID:
  PubChem CID: 3062316
  ChEBI ID: CHEBI:49375
  CAS Number: 302962-49-8
  TTD ID: D0E6XR
  VARIDT ID: DR00182
  INTEDE ID: DR0423
  ACDINA ID: D00171

Full List of Drug Formulations Containing This Drug

Dasatinib 100 mg tablet

Company	Formulation ID	FDA Description
E.R. Squibb & Sons	F05270	Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified

Dasatinib 140 mg tablet

Company	Formulation ID	FDA Description
E.R. Squibb & Sons	F05271	Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified

Dasatinib 20 mg tablet

Company	Formulation ID	FDA Description
E.R. Squibb & Sons	F05272	Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified

Dasatinib 50 mg tablet

Company	Formulation ID	FDA Description
E.R. Squibb & Sons	F05273	Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified

Dasatinib 70 mg tablet

Company	Formulation ID	FDA Description
E.R. Squibb & Sons	F05274	Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
Physicians Total Care	F05275	Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols

Dasatinib 80 mg tablet

Company	Formulation ID	FDA Description
E.R. Squibb & Sons	F05276	Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified

References

• [1] Dasatinib FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5678).
• [3] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [4] Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.