Details of the Drug Formulations

General Information of Drug (ID: DMPI98T)

• Drug Name: Doxepin Drug Info
• Synonyms: Zonalon; doxepin; Doxepine; Doxepinum [INN-Latin]; Doxepina [INN-Spanish]; Doxepin [USAN]; trans-doxepin; (e)-doxepin; 1668-19-5; Quitaxon; MF 10; UNII-851NLB57HQ; Sinequan; CCRIS 9176; HSDB 3069; Sinequan (TN); Cidoxepina; Cidoxepinum; 851NLB57HQ; 11-(3-(Dimethylamino)propylidene)-6H-dibenz(b,e)oxepine; 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz(b,e)oxipin; 11-(3-Dimethylamino-propyliden)-6,11-dihydro-dibenz(b,e)oxipin; N,N-Dimethyldibenz(b,e)oxepin-delta(11(6H),gamma)-propylamine; Cidoxepin [INN]; Curatin; Adapin; Cidoxepin; Doxepina; Doxepinum; Triadapin; Doxepin Hydrochloride; MOLI001594; Adapine (TN); Aponal (TN); Cis-doxepin; Deptran (TN); Doxepin (INN); Doxepin, Hydrochloride; Sinquan (TN); Xepin (TN); Zonalon (TN); Doxepin (Z)-isomer; Cis-N-(3-(6H-Dibenz(b,e)oxepin-11-yliden)propyl)-N,N-dimethylamin; (3E)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine; (3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine; (3Z)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-di(methyl)propan-1-amine; (3Z)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine; (3Z)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine; (Z)-Doxepin; 3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine; 3-Dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine; 3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine; [11C]doxepin

Indication

Disease Entry	ICD 11	Status	REF
Anxiety		Approved	[1]
Bipolar depression		Approved	[1]
Depression	6A70-6A7Z	Approved	[2]
Insomnia	7A00-7A0Z	Approved	[1]
Pruritus	EC90	Investigative	[1]

• Therapeutic Class: Antidepressants
• Cross-matching ID:
  PubChem CID: 667477
  CAS Number: 1668-19-5
  TTD ID: D06FES
  VARIDT ID: DR00542
  INTEDE ID: DR0544
  ACDINA ID: D00626

Full List of Drug Formulations Containing This Drug

Sinequan 10 mg capsule

Company	Formulation ID	FDA Description
Lake Eire Medical & Surgical Supply DBA Quality Care Products; Stat Rx USA	F20227	Sodium lauryl sulfate; D&c yellow no. 10; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Rebel Distributors	F20226	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Aidarex Pharmaceuticals; Aphena Pharma Solutions-Tennessee; Medsource Pharmaceuticals; Mylan Pharamceuticals; RemedyRepack	F20228	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Bryant Ranch Prepack	F20229	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Microcrystalline cellulose; Shellac; Starch, corn
Physicians Total Care	F20230	D&c orange no. 10; Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Gelatin; Starch, corn
Amneal Pharmaceuticals	F20225	Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Par Pharmaceutical	F20224	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Gelatin; Starch, corn

Sinequan 50 mg capsule

Company	Formulation ID	FDA Description
H. J. Harkins Company; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Stat Rx USA	F20253	Sodium lauryl sulfate; D&c yellow no. 10; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
RemedyRepack	F20251	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Modified corn starch (1-octenyl succinic anhydride); Shellac
Rebel Distributors	F20252	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
A-S Medication Solutions; DirectRX; Mylan Pharamceuticals; PD-Rx Pharmaceuticals; RemedyRepack	F20254	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
A-S Medication Solutions; Bryant Ranch Prepack; Unit Dose Services	F20255	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Microcrystalline cellulose; Shellac; Starch, corn
Physicians Total Care	F20249	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Titanium dioxide; Gelatin; Starch, corn
Amneal Pharmaceuticals	F20250	Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Par Pharmaceutical	F20248	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Gelatin; Starch, corn

Sinequan 25 mg capsule

Company	Formulation ID	FDA Description
RemedyRepack	F20243	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Modified corn starch (1-octenyl succinic anhydride)
PD-Rx Pharmaceuticals	F20244	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Aphena Pharma Solutions-Tennessee; DirectRX; Mylan Pharamceuticals; RemedyRepack	F20245	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Cardinal Health	F20246	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Bryant Ranch Prepack	F20247	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Microcrystalline cellulose; Shellac; Starch, corn
Physicians Total Care	F20241	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Titanium dioxide; Gelatin; Starch, corn
Amneal Pharmaceuticals	F20242	Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Par Pharmaceutical	F20240	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Gelatin; Starch, corn

Sinequan 100 mg capsule

Company	Formulation ID	FDA Description
Stat Rx USA	F20233	Sodium lauryl sulfate; D&c yellow no. 10; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Fd&c green no. 3; Gelatin; Shellac; Starch, corn
RemedyRepack	F20232	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Fd&c green no. 3; Gelatin; Modified corn starch (1-octenyl succinic anhydride); Shellac
Medsource Pharmaceuticals; Mylan Pharamceuticals; RemedyRepack	F20234	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Fd&c green no. 3; Gelatin; Shellac; Starch, corn
Physicians Total Care	F20235	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Fd&c green no. 3; Gelatin; Starch, corn
Amneal Pharmaceuticals	F20231	Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Fd&c green no. 3; Gelatin; Shellac; Starch, corn
Par Pharmaceutical	F20236	Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Fd&c green no. 3; Gelatin; Starch, corn

Sinequan 75 mg capsule

Company	Formulation ID	FDA Description
RemedyRepack	F20257	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Fd&c green no. 3; Gelatin; Shellac; Starch, corn
Avera McKennan Hospital; Mylan Pharamceuticals; PD-Rx Pharmaceuticals; RemedyRepack; TYA Pharmaceuticals	F20258	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Fd&c green no. 3; Gelatin; Shellac; Starch, corn
Physicians Total Care	F20259	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Titanium dioxide; Fd&c green no. 3; Gelatin; Starch, corn
Amneal Pharmaceuticals	F20256	Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Fd&c green no. 3; Gelatin; Shellac; Starch, corn
Par Pharmaceutical	F20260	Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Fd&c green no. 3; Gelatin; Starch, corn

Sinequan 150 mg capsule

Company	Formulation ID	FDA Description
AvKARE	F20237	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Gelatin; Shellac; Starch, corn
Physicians Total Care; RemedyRepack; Stat Rx USA	F20238	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Gelatin; Starch, corn
Par Pharmaceutical	F20239	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Gelatin; Starch, corn

Sinequan 6 mg tablet

Company	Formulation ID	FDA Description
Pernix Therapeutics	F20223	D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline

Sinequan 3 mg tablet

Company	Formulation ID	FDA Description
Pernix Therapeutics	F20222	Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline

References

• [1] Doxepin FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1225).