Details of the Drug Formulations

General Information of Drug (ID: DMRJFN9)

• Drug Name: Theophylline Drug Info
• Synonyms: Bronchoretard; Cetraphylline; Chronophyllin; Dimethylxanthine; Elixophylline; Liquophylline; Pseudotheophylline; Afonilum Retard; Bronchodid Duracap; Elixophyllin SR; Somophyllin CRT; Spophyllin retard; Telbans DrySyrup; Teofilina [Polish]; Theal tablets; Theobid Duracap; Theodur Dry Syrup; Uniphyllin continus; Elixophyllin (TN); Elixophyllin(e); Pulmo-Timelets; Somophyllin-CRT; Somophyllin-DF; Theo-Organidin; Theoclear-200; Theodur G (TN); Theolair (TN); Theophylline (JP15); Theophylline-SR; Quibron-t (TN); Theo-Dur-Sprinkle; Theophylline-[8-3H; Theoclear L.A.-130; 1,3 Dimethylxanthine; 1,3-Dimethylxanthine; 1H-purine-2,6-dione

Indication

Disease Entry	ICD 11	Status	REF
Bronchitis	CA20	Approved	[1]
Chronic obstructive pulmonary disease	CA22	Approved	[2]
Lung cancer	2C25.0	Approved	[1]
Non-small-cell lung cancer	2C25.Y	Approved	[1]
Pulmonary disease	1B10-1F85	Approved	[1]
Pulmonary emphysema	CA21.Z	Approved	[1]
Severe asthma	CA23	Approved	[1]
Asthma	CA23	Investigative	[1]

• Therapeutic Class: Bronchodilator Agents
• Cross-matching ID:
  PubChem CID: 2153
  ChEBI ID: CHEBI:28177
  CAS Number: 58-55-9
  TTD ID: D0F8RA
  VARIDT ID: DR00191
  INTEDE ID: DR1575
  ACDINA ID: D00670

Full List of Drug Formulations Containing This Drug

Theophylline 300 mg capsule

Company	Formulation ID	FDA Description
Cardinal Health	F21044	D&c yellow no. 10; Fd&c red no. 40; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Shellac; Starch, corn
UCB	F21043	D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Shellac

Theophylline 200 mg capsule

Company	Formulation ID	FDA Description
UCB	F21036	D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Ethylcelluloses; Gelatin; Shellac

Theophylline 400 mg capsule

Company	Formulation ID	FDA Description
UCB	F21052	D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Shellac

Theophylline 100 mg capsule

Company	Formulation ID	FDA Description
UCB	F21034	D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Shellac

Theophylline 200 mg tablet

Company	Formulation ID	FDA Description
NCS HealthCare of KY, Inc dba Vangard Labs	F21038	Anhydrous lactose; Magnesium stearate; Hypromellose; Povidone
State of Florida DOH Central Pharmacy	F21039	Glyceryl behenate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline
Lake Eire Medical & Surgical Supply DBA Quality Care Products; Major Pharmaceuticals; Physicians Total Care; RemedyRepack	F21040	Anhydrous lactose; Magnesium stearate; Povidone; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (100000 mpa.s)
AvKARE; Pliva; Preferred Pharamaceuticals	F21037	Anhydrous lactose; Magnesium stearate; Povidone k30; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (100000 mpa.s)
Bryant Ranch Prepack	F21041	Anhydrous lactose; Magnesium stearate; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (100000 mpa.s); Povidones
American Health Packaging	F21042	Anhydrous lactose; Magnesium stearate; Hypromelloses; Povidones

Theophylline 300 mg tablet

Company	Formulation ID	FDA Description
NCS HealthCare of KY, Inc dba Vangard Labs	F21045	Anhydrous lactose; Magnesium stearate; Hypromellose; Povidone
State of Florida DOH Central Pharmacy	F21046	Glyceryl behenate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline
Lake Eire Medical & Surgical Supply DBA Quality Care Products; Major Pharmaceuticals; Physicians Total Care	F21047	Anhydrous lactose; Magnesium stearate; Povidone; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (100000 mpa.s)
RemedyRepack	F21051	Anhydrous lactose; Magnesium stearate; Povidone; Hypromelloses
AvKARE; Bryant Ranch Prepack; Pliva	F21049	Anhydrous lactose; Magnesium stearate; Povidone k30; Hypromellose 2208 (100 mpa.s)
Alembic Pharmaceuticals; Heritage Pharmaceuticals; State of Florida DOH Central Pharmacy	F21050	Lactose monohydrate; Magnesium stearate; Povidone k30; Hypromelloses
A-S Medication Solutions; Clinical Solutions Wholesale	F21048	Anhydrous lactose; Magnesium stearate; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (100000 mpa.s); Povidones

Theophylline 400 mg tablet

Company	Formulation ID	FDA Description
Rhodes Pharmaceuticals	F21053	Cetostearyl alcohol; Magnesium stearate; Talc; Povidone; Hydroxyethyl cellulose (2000 cps at 1%)
Mylan Pharamceuticals	F21055	Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Glyceryl behenate/eicosadioate
Glenmark Pharmaceutials	F21054	Cetostearyl alcohol; Magnesium stearate; Talc; Hydroxyethyl cellulose (4000 mpa.s at 1%); Povidones
Bryant Ranch Prepack; Carilion Materials Management	F21056	Cetostearyl alcohol; Magnesium stearate; Talc; Hydroxyethyl cellulose (2000 mpa.s at 1%); Povidone, unspecified

Theophylline 600 mg tablet

Company	Formulation ID	FDA Description
Rhodes Pharmaceuticals	F21059	Cetostearyl alcohol; Magnesium stearate; Talc; Povidone; Hydroxyethyl cellulose (2000 cps at 1%)
Mylan Pharamceuticals	F21061	Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Glyceryl behenate/eicosadioate
Glenmark Pharmaceutials	F21060	Cetostearyl alcohol; Magnesium stearate; Talc; Hydroxyethyl cellulose (4000 mpa.s at 1%); Povidones

Theophylline 100 mg tablet

Company	Formulation ID	FDA Description
AvKARE; Bryant Ranch Prepack; Major Pharmaceuticals; Physicians Total Care; Pliva	F21035	Anhydrous lactose; Magnesium stearate; Povidone k30; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (100000 mpa.s)

Theophylline 450 mg tablet

Company	Formulation ID	FDA Description
Pliva	F21057	Anhydrous lactose; Magnesium stearate; Povidone k30; Hypromellose 2208 (100 mpa.s)
Alembic Pharmaceuticals; Heritage Pharmaceuticals	F21058	Lactose monohydrate; Magnesium stearate; Povidone k30; Hypromelloses

References

• [1] Theophylline FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 413).