Details of the Drug Formulations

General Information of Drug (ID: DMTBGW8)

• Drug Name: Vardenafil Drug Info
• Synonyms: VDN; Levitra (TN); VARDENAFIL, LEVITRA; Vardenafil (INN); 1-((3-(3,4-Dihydro-5-methyl-4-oxo-7-propylimidazo(5,1-f)-as-triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethylpiperazine; 2-(2-Ethoxy-5-(4-ethylpiperazin-1-yl-1-sulfonyl)phenyl)-5-methyl-7-propyl-3H-imidazo(5,1-f)(1,2,4)triazin-4-one; 2-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one; 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE; 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4-ol

Indication

Disease Entry	ICD 11	Status	REF
Cystic fibrosis	CA25	Approved	[1]
Erectile dysfunction	HA01.1	Approved	[2]

• Therapeutic Class: Antiimpotence Agents
• Cross-matching ID:
  PubChem CID: 135400189
  ChEBI ID: CHEBI:46295
  CAS Number: 224785-90-4
  TTD ID: D0C9SY
  VARIDT ID: DR00169
  INTEDE ID: DR1673
  ACDINA ID: D00721

Full List of Drug Formulations Containing This Drug

Vardenafil 10 mg tablet

Company	Formulation ID	FDA Description
Physicians Total Care	F22136	Aspartame; Magnesium stearate; Mannitol; Sorbitol; Crospovidone; Silicon dioxide
GlaxoSmithKline	F22135	Aspartame; Magnesium stearate; Mannitol; Sorbitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%)
Aphena Pharma Solutions-Tennessee; PD-Rx Pharmaceuticals; Physicians Total Care	F22138	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
GlaxoSmithKline	F22137	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified

Vardenafil 20 mg tablet

Company	Formulation ID	FDA Description
Aphena Pharma Solutions-Tennessee; Kaiser Foundation Hospitals; Physicians Total Care	F22141	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
Bryant Ranch Prepack; PD-Rx Pharmaceuticals	F22142	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
GlaxoSmithKline	F22140	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified

Vardenafil 5 mg tablet

Company	Formulation ID	FDA Description
Aphena Pharma Solutions-Tennessee	F22144	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
GlaxoSmithKline	F22143	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified

Vardenafil 2.5 mg tablet

Company	Formulation ID	FDA Description
GlaxoSmithKline	F22139	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified

References

• [1] Vardenafil FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7320).