General Information of Drug (ID: DMTM2IK)

Drug Name
Mercaptopurine Drug Info
Synonyms
6-mercaptopurine; Ismipur; Leukerin; Leupurin; Mercaleukim; Mercaleukin; Mercaptopurin; Mercaptopurina; Mercaptopurinum; Mercapurin; Merkaptopuryna; Mern; Purimethol; Purinethiol; Purinethol; Thiopurine; Leupu rin; Mercaptopurin [German]; Mercaptopurina Wellcome; Mercaptopurine anhydrous; Merkaptopuryna [Polish]; Puri Nethol; BW 57 323H; Glaxo Wellcome Brand of 6 Mercaptopurine; GlaxoSmithKline Brand of 6 Mercaptopurine; M0063; NCIMech_000025; PM6; Wellcome Brand of 6 Mercaptopurine; Glaxo Wellcome Brand of 6-Mercaptopurine; GlaxoSmithKline Brand of 6-Mercaptopurine; Mercaptopurina [INN-Spanish]; Mercaptopurine (INN); Mercaptopurine (VAN); Mercaptopurine (anhydrous); Mercaptopurinum [INN-Latin]; Puri-Nethol; Purineantimetabolite: inhibits nucleic acid replication; Purinethol (TN); U-4748; Wellcome Brand of 6-Mercaptopurine; AG-670/31547064; Purine-6-thiol; Leukerin, 99%-Carc; Purine-6(1H)-thione; Purinethol, 6-mercaptopurine, 6-MP, Mercaptopurine; 6 MP; 6 Mercaptopurine Monohydrate; 6 Thiohypoxanthine; 6 Thiopurine; 6-MERCAPTOPURINE MONOHYDRATE; 6-MP; 6-Mercaptopurin; 6-Merkaptopurin; 6-Merkaptopurin [Czech]; 6-Purinethiol; 6-Thiohypoxanthine; 6-Thiopurine; 6-Thioxopurine; Mercaptopurine (Purine analog)
Indication
Disease Entry ICD 11 Status REF
Acute lymphoblastic leukaemia 2A85 Approved [1]
Acute lymphocytic leukaemia 2B33.3 Approved [2]
Crohn disease DD70 Phase 4 [3]
Middle East Respiratory Syndrome (MERS) 1D64 Preclinical [4]
Severe acute respiratory syndrome (SARS) 1D65 Preclinical [4]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
667490
ChEBI ID
CHEBI:2208
CAS Number
50-44-2
TTD ID
D09UZO
VARIDT ID
DR00145
INTEDE ID
DR1031
ACDINA ID
D00399

Full List of Drug Formulations Containing This Drug

Mercaptopurine 50 mg tablet
Company Formulation ID FDA Description
RemedyRepack F13037 Stearic acid; Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn; Starch, potato
Avera McKennan Hospital; West-Ward Pharmaceticals F13038 Stearic acid; Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn; Starch, potato
Gate Pharmaceuticals; Teva Pharmaceuticals F13040 Stearic acid; Lactose; Magnesium stearate; Starch, corn; Starch, potato
Quinn Pharmaceuticals F13041 Stearic acid; Lactose monohydrate; Magnesium stearate; Starch, corn; Starch, potato
Par Pharmaceutical; Physicians Total Care F13042 Stearic acid; Lactose; Silicon dioxide; Cellulose, microcrystalline
Mylan Pharamceuticals F13039 Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Starch, corn
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⏷ Show the Full List of 6 Formulation(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7226).
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 ClinicalTrials.gov (NCT00846703) The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia. U.S. National Institutes of Health.
4 Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus. Antiviral Res. 2015 Mar;115:9-16.