Details of the Drug Formulations

General Information of Drug (ID: DMVS9WQ)

Drug Name
Nitisinone Drug Info
Synonyms
Nitisinona; Nitisinonum; Nitisone; Orfadin; Nitisinone [INN]; SC 0735; FE-0200; Nitisinone (NTBC); Nitisinone [USAN:INN]; Orfadin (TN); Nitisinone (JAN/USAN/INN); 2-(2-Nitro-4-trifluoromethylbenzoyl)cyclohexane-1,3-dione; 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione; 2-(Alpha,alpha,alpha-trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedione; 2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione; 2-{[2-nitro-4-(trifluoromethyl)phenyl]carbonyl}cyclohexane-1,3-dione
Indication
Disease Entry ICD 11 Status REF
Hereditary tyrosinemia type 1 5C50.11 Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
115355
ChEBI ID
CHEBI:50378
CAS Number
104206-65-7
TTD ID
D0V1UW
ACDINA ID
D00474

Full List of Drug Formulations Containing This Drug

Nitisinone 10 mg tablet
Company Formulation ID FDA Description
Cycle Pharmaceuticals F15411 Lactose monohydrate; Glyceryl dibehenate
------------------------------------------------------------------------------------
Nitisinone 2 mg tablet
Company Formulation ID FDA Description
Cycle Pharmaceuticals F15414 Lactose monohydrate; Glyceryl dibehenate
------------------------------------------------------------------------------------
Nitisinone 5 mg tablet
Company Formulation ID FDA Description
Cycle Pharmaceuticals F15418 Lactose monohydrate; Glyceryl dibehenate
------------------------------------------------------------------------------------
Nitisinone 10 mg capsule
Company Formulation ID FDA Description
Rare Disease Therapeutics F15409 Titanium dioxide; Gelatin
Swedish Orphan Biovitrum AB F15410 Titanium dioxide; Gelatin; Starch, corn
------------------------------------------------------------------------------------
Nitisinone 2 mg capsule
Company Formulation ID FDA Description
Rare Disease Therapeutics F15412 Titanium dioxide; Gelatin
Swedish Orphan Biovitrum AB F15413 Titanium dioxide; Gelatin; Starch, corn
------------------------------------------------------------------------------------
Nitisinone 20 mg capsule
Company Formulation ID FDA Description
Swedish Orphan Biovitrum AB F15415 Titanium dioxide; Gelatin; Starch, corn
------------------------------------------------------------------------------------
Nitisinone 5 mg capsule
Company Formulation ID FDA Description
Rare Disease Therapeutics F15416 Titanium dioxide; Gelatin
Swedish Orphan Biovitrum AB F15417 Titanium dioxide; Gelatin; Starch, corn
------------------------------------------------------------------------------------

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6834).