Details of the Drug Formulations

General Information of Drug (ID: DMWH7NQ)

Drug Name

Alprostadil Drug Info

Synonyms

Prostaglandin E1; alprostadil; 745-65-3; PGE1; Muse; Edex; Caverject; Prostin VR; Alprostadilum; Femprox; Befar; Vitaros; Prostandin; Liprostin; PGE-1; Prink (TN); Befar (TN); Prostavasin; Vasaprostan; MR-256; Minprog; UNII-F5TD010360; Alprostadil(Caverject); CHEMBL495; (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid; Prostivas; Lipoprost; 11alpha,15alpha-Dihydroxy-9-oxo-13-trans-prostenoic acid; (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate; FemLife; RayVa; Sugiran; Viridal; MR 256; PGE1 Oligomer; BML1-F06; Caverject (TN); Edex (TN); HEI-507; Muse (TN); Prostin VR pediatric (TN); U-10136; Alprostadil (JP15/USP/INN); Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11alpha,13E,15S)-, homopolymer; (11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid; (13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-oic acid; 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid; Lipo-alprostadil

Indication

Disease Entry	ICD 11	Status	REF
Aorta coarctation		Approved	[1]
Diabetic foot ulcer	BD54	Approved	[2]
Erectile dysfunction	HA01.1	Approved	[3]
Pulmonary hypertension	BB01	Approved	[1]
Tetralogy of fallot		Approved	[1]

Therapeutic Class

Vasodilator Agents

Cross-matching ID

PubChem CID: 5280723
ChEBI ID: CHEBI:15544
CAS Number: 745-65-3
TTD ID: D0I4DQ
VARIDT ID: DR00210
INTEDE ID: DR1923
ACDINA ID: D00828

Full List of Drug Formulations Containing This Drug

Alprostadil 0.01mg/vial injectable

Company	Formulation ID	FDA Description
Pfizer	F23614	Alpha Cyclodextrin; Lactose; Sodium Citrate; Benzyl Alcohol; Hydrochloric Acid; Sodium Hydroxide
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Alprostadil 0.005mg/vial injectable

Company	Formulation ID	FDA Description
Auxilium Pharmaceuticals	F23615	Sodium Chloride; -Cyclodextrin; Lactose
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References

1	Alprostadil FDA Label
2	Emerging drugs for diabetic foot ulcers. Expert Opin Emerg Drugs. 2006 Nov;11(4):709-24.
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1882).