Details of the Drug-Related molecule(s) Activity Atlas

General Information of Drug (ID: DMRICNP)

Drug Name
Vandetanib Drug Info
Synonyms
Zactima; Vandetanib [INN]; CH 331; ZD 6474; ZD6474; AZD-6474; CH-331; F9995-0087; ZD-6474; Zactima, ZD6474; Vandetanib (JAN/INN); Vandetanib, Zactima, ZD6474; N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; Vandetanib (Pan-TK inhibitor)
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
3081361
ChEBI ID
CHEMBL24828
CAS Number
CAS 443913-73-3
TTD ID
D0G6QF
VARIDT Drug ID
DR00618
INTEDE Drug ID
DR1669
ACDINA Drug ID
D00720

Molecule-level Activity Landscape of This Drug
Molecule Name Gene Name UniProt ID Type IC50 (nM) Details
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Molecule Name Gene Name UniProt ID Type Kd (nM) Details
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Molecule Name Gene Name UniProt ID Type Ki (nM) Details
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Experimental Drug Sensitivity Data Across Cancer Cell Lines
Cell Line Related Disease IC50 (Log₂ µM) Original Dataset Details
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Cytotoxic Activity Landscape of This Drug

Cell Line Disease Value (nM) ChEMBL Assay ID Details
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