Details of the Drug-Related molecule(s) Activity Atlas

General Information of Drug (ID: DMWPMN2)

• Drug Name: SAR 444727 Drug Info
• Synonyms: atuzabrutinib; Atuzabrutinib [INN]; YZ68ZB8LWA; UNII-YZ68ZB8LWA; PRN473; CHEMBL4114766; PRN-473; SAR444727; SAR-444727; 1581714-49-9; (alphaE,3R)-3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1hpyrazolo(3,4-d)pyrimidin-1-yl)-alpha-(2,2-dimethylpropylidene)-beta-oxo-1-piperidinepropanenitrile; 1-Piperidinepropanenitrile, 3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)-alpha-(2,2-dimethylpropylidene)-beta-oxo-, (alphaE,3R)-; 1-Piperidinepropanenitrile, 3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-alpha-(2,2-dimethylpropylidene)-beta-oxo-, (alphaE,3R)-; ATUZABRUTINIB [USAN]; SCHEMBL15515897; SCHEMBL15516108; GTPL11666; BDBM197260; BDBM50589191; AKOS040756908; compound 11 [PMID: 35302767]; HY-132808; CS-0204055; US9090621, 125A; (2E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4,4-dimethylpent-2-enenitrile; (alphaE,3R)-3-[4-Amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-alpha-(2,2-dimethylpropylidene)-beta-oxo-1-piperidinepropanenitrile; (E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4,4-dimethylpent-2-enenitrile
• Cross-matching ID:
  PubChem CID: 73438222
  ChEBI ID: CHEMBL4114766
  TTD ID: DS6V8H

Molecule-level Activity Landscape of This Drug

IC50 (17) Download

Molecule Name	Gene Name	UniProt ID	Type	IC50 (nM)	Details
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