Details of the Drug-Related molecule(s) Activity Atlas

General Information of Drug (ID: DMYLT67)

• Drug Name: TKI258 Drug Info
• Synonyms: Dovitinib; 405169-16-6; CHIR-258; TKI-258; Chir 258; 4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one; CHIR258; Dovitinib (TKI-258, CHIR-258); UNII-I35H55G906; CHEMBL522892; 804551-71-1; I35H55G906; TKI 258; 1027263-12-2; (3Z)-4-Amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1,3-dihydro-2H-benzimidazol-2-ylidene]-2(3H)-quinolinone; C21H21FN6O; 4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one
• Therapeutic Class: Anticancer Agents
• Cross-matching ID:
  PubChem CID: 135611162
  CAS Number: CAS 915769-50-5
  TTD ID: D07OZR
  INTEDE Drug ID: DR1815

Molecule-level Activity Landscape of This Drug

IC50 (28) EC50 (5) Kd (286) Ki (148) Download

Molecule Name	Gene Name	UniProt ID	Type	IC50 (nM)	Details
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Molecule Name	Gene Name	UniProt ID	Type	EC50 (nM)	Details
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Molecule Name	Gene Name	UniProt ID	Type	Kd (nM)	Details
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Molecule Name	Gene Name	UniProt ID	Type	Ki (nM)	Details
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Experimental Drug Sensitivity Data Across Cancer Cell Lines

Cell Line	Related Disease	IC50 (Log₂ µM)	Original Dataset	Details
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Cytotoxic Activity Landscape of This Drug

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Cell Line	Disease	Value (nM)	ChEMBL Assay ID	Details
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