Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM0KUMX)

Drug Name

2-(4-methoxyphenyl)-4,5-dihydro-1H-imidazole Drug Info

Synonyms

2-(4-Methoxyphenyl)-4,5-dihydro-1H-imidazole; 6302-84-7; 4,5-Dihydro-2-(4-methoxyphenyl)-1H-Imidazole; 2-Imidazoline, 2-(p-methoxyphenyl)-; 1H-Imidazole, 4,5-dihydro-2-(4-methoxyphenyl)-; CHEMBL13633; NSC41538; AC1L5ZGN; 2-(p-Anisyl)-1-imidazoline; SCHEMBL9575256; AC1Q580G; CTK5B7166; DTXSID40285359; LPRQSQCAHSRGRZ-UHFFFAOYSA-N; ZINC1672770; BDBM50240364; NSC-41538; AKOS022491172; MCULE-4518622050; 1-(2-imidazolin-2-yl)-4-methoxybenzene; 2-(P-METHOXY-PHENYL)-IMIDAZOLINE; DB-073247; KB-222983; ST50998435; FT-0712566

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 237746
CAS Number: CAS 6302-84-7
TTD Drug ID: DM0KUMX

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type A (MAO-A)	TT3WG5C	AOFA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type A (MAO-A)	DTT	MAOA	7.207	8.159	9.043	7.711

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type A (MAO-A)	DTT	MAOA	8.14E-01	0.05	0.1

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Ultrasound promoted synthesis of 2-imidazolines in water: a greener approach toward monoamine oxidase inhibitors. Bioorg Med Chem Lett. 2009 Jan 15;19(2):546-9.