Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM1V83P)

Drug Name

N-(4-(2-aminoethyl)phenyl)benzenesulfonamide Drug Info

Synonyms

N-[4-(2-aminoethyl)phenyl]Benzenesulfonamide; CHEMBL434365; N-(4-(2-aminoethyl)phenyl)benzenesulfonamide; 159182-12-4; N-(4-[2-Aminoethyl]phenyl)Benzenesulfonamide; SCHEMBL5830405; PRODIAPRPOSQSM-UHFFFAOYSA-N; ZINC20224442; BDBM50193473; AKOS011587141; MCULE-5428014421; DA-09746; FT-0710145; N-(4-[2-aminoethyl]phenyl) benzenesulfonamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 15281645
TTD Drug ID: DM1V83P

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 6 receptor (HTR6)	TTJS8PY	5HT6R_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
5-HT 6 receptor (HTR6)	DTT	HTR6	5.594	5.781	5.271	3.963

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
5-HT 6 receptor (HTR6)	DTT	HTR6	1.23E-05	-0.12	-0.71

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors. J Med Chem. 2006 Aug 24;49(17):5217-25.