Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM23E0R)

Drug Name

4-Inden-(1E)-ylidenemethyl-phenylamine Drug Info

Synonyms

4-(1H-Inden-1-ylidenemethyl)aniline; NSC83092; 4-[(E)-inden-1-ylidenemethyl]aniline; CHEMBL193376; 487-61-6; 1-(4-Aminobenzylidene)indene; p-Toluidine, .alpha.-inden-1-ylidene-; 4-(1H-Inden-1-ylidenemethyl)phenylamine; Benzenamine, 4-(1H-inden-1-ylidenemethyl)-; MLS002694146; WLN: L56 BYJ BU1R DZ; 4-Inden-(1E)-ylidenemethyl-phenylamine; AC1O53IW; AC1Q1HQ2; cid_98148; BDBM50164749; NSC-83092; AKOS030547084; ZINC100425076; NCGC00186285-13; NCGC00186285-07; NCGC00186285-06; NCGC00186285-01; NCGC00186285-11; NCGC00186285-09

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6476992
CAS Number: CAS 487-61-6
TTD Drug ID: DM23E0R

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 6 receptor (HTR6)	TTJS8PY	5HT6R_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
5-HT 6 receptor (HTR6)	DTT	HTR6	5.594	5.781	5.271	3.963

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
5-HT 6 receptor (HTR6)	DTT	HTR6	1.23E-05	-0.12	-0.71

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Binding of isotryptamines and indenes at h5-HT6 serotonin receptors. Bioorg Med Chem Lett. 2005 Apr 15;15(8):1987-91.