General Information of Drug (ID: DM27GH0)

Drug Name
23-hydroxybetulinic acid Drug Info
Synonyms
85999-40-2; CHEBI:69580; 3,23-dihydroxy-20(29)-lupen-28-oic acid; Anemosapogenin; 23-Hydroxybetulinicacid; 23-hydroxy betulic acid; CHEMBL251308; 23-Hydroxybetulinic Acid, 25; BDBM23209; MolPort-039-338-114; HXWLKAXCQLXHML-WGOZWDAUSA-N; HY-N0566; EBD870843; ZINC14980302; AKOS032944876; CS-5686; SC-72875; 23-Hydroxybetulinic acid, > 3I(2),23-dihydroxylup-20(29)-en-28-oic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
21672692
ChEBI ID
CHEBI:69580
CAS Number
CAS 85999-40-2
TTD Drug ID
DM27GH0

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glycogen phosphorylase muscle form (GP) TTZHY6R PYGM_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Glycogen phosphorylase muscle form (GP) DTT PYGM 4.036 5.34 6.256 6.062
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glycogen phosphorylase muscle form (GP) DTT PYGM 2.69E-01 -0.23 -0.14
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystal... J Med Chem. 2008 Jun 26;51(12):3540-54.