Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM2K5VP)

Drug Name
Coxsackievirus A21 Drug Info
Synonyms Cavatak (TN)
Indication
Disease Entry ICD 11 Status REF
Glioblastoma multiforme 2A00.0 Phase 2 [1]
Bladder cancer 2C94 Phase 1/2 [2]
Lung cancer 2C25.0 Phase 1/2 [2]
Melanoma 2C30 Phase 1/2 [2]
Prostate cancer 2C82.0 Phase 1/2 [2]
Cross-matching ID
TTD Drug ID
DM2K5VP

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement decay-accelerating factor (CD55) TT5Z9WY DAF_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Complement decay-accelerating factor (CD55) DTT CD55 6.754 6.394 5.638 7.012
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Glioblastoma multiforme
ICD Disease Classification 2A00.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement decay-accelerating factor (CD55) DTT CD55 2.44E-02 2.16 3.38
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Oncolytic Coxsackievirus A21 as a novel therapy for multiple myeloma. Br J Haematol. 2007 Apr;137(2):133-41.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)