Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM2QBDS)

Drug Name
Disitertide Drug Info
Synonyms NAFB-001; Disitertide cream (skin disorders), Digna
Indication
Disease Entry ICD 11 Status REF
Macular degeneration 9B78.3 Phase 2 [1]
Cross-matching ID
PubChem CID
9833838
CAS Number
CAS 272105-42-7
TTD Drug ID
DM2QBDS

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Transforming growth factor beta 1 (TGFB1) TTR9XHZ TGFB1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Transforming growth factor beta 1 (TGFB1) DTT TGFB1 5.844 5.859 6.44 6.172
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Macular degeneration
ICD Disease Classification 9B78.3
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Transforming growth factor beta 1 (TGFB1) DTT TGFB1 5.95E-09 1.68 7.81
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Perspectives of TGF-beta inhibition in pancreatic and hepatocellular carcinomas. Oncotarget. 2014 January; 5(1): 78-94.