Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM310ES)

Drug Name
N-(naphthylamino)-benzoate derivative 1 Drug Info
Synonyms PMID28895472-Compound-28
Cross-matching ID
PubChem CID
56851703
ChEBI ID
CHEMBL2023820
TTD Drug ID
DM310ES

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dihydrodiol dehydrogenase type I (AKR1C3) TT5ZWB6 AK1C3_HUMAN Inhibitor; Antagonist; Blocker [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Dihydrodiol dehydrogenase type I (AKR1C3) DTT AKR1C3 9.375 10.135 10.108 10.14
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Dihydrodiol dehydrogenase type I (AKR1C3) DTT AKR1C3 4.06E-01 1.39 0.74
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Dec;27(12):1329-1340.