Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM3PEUN)

Drug Name
Dihydropyrido pyrazinone compound 3 Drug Info
Synonyms PMID26924192-Compound-60
Cross-matching ID
TTD Drug ID
DM3PEUN

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Polo-like kinase 1 (PLK1) TTIYVQP PLK1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Polo-like kinase 1 (PLK1) DTT PLK1 4.492 5.573 4.555 2.459
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Polo-like kinase 1 (PLK1) DTT PLK1 4.16E-07 -0.38 -0.72
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 BET inhibitors in cancer therapeutics: a patent review.Expert Opin Ther Pat. 2016;26(4):505-22.