Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM3TRF7)

Drug Name
Brasofensine Drug Info
Synonyms Brasofensine [INN]
Indication
Disease Entry ICD 11 Status REF
Parkinson disease 8A00.0 Phase 2 [1]
Cross-matching ID
PubChem CID
9554198
CAS Number
CAS 171655-91-7
TTD Drug ID
DM3TRF7

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serotonin transporter (SERT) TT3ROYC SC6A4_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Serotonin transporter (SERT) DTT SLC6A4 6.278 5.469 6.075 6.966
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Parkinson disease
ICD Disease Classification 8A00.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Serotonin transporter (SERT) DTT SLC6A4 8.76E-01 7.18E-05 6.19E-04
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Brasofensine NeuroSearch. Curr Opin Investig Drugs. 2000 Dec;1(4):504-7.