Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM48Y9E)

Drug Name

JNJ-38158471 Drug Info

Synonyms

VEGFR-2 inhibitors (angiogenesis disorder/cancer); VEGFR-2 inhibitors (angiogenesis disorder/cancer), Johnson & Johnson

Indication

Disease Entry	ICD 11	Status	REF
Angiogenesis disorder	BE2Z	Investigative	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Vascular endothelial growth factor receptor 2 (KDR)	TTUTJGQ	VGFR2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Angiogenesis disorder

ICD Disease Classification

BE2Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Vascular endothelial growth factor receptor 2 (KDR)	DTT	KDR	1.98E-01	0.11	0.2

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1813).