Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM4A0NP)

Drug Name

SOPHORICOSIDE Drug Info

Synonyms

Sophoricoside; 152-95-4; UNII-J0407L5MGM; J0407L5MGM; CHEMBL486626; 5,7-dihydroxy-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one; 5',7'-Dihydroxy-4'-glucosyloxyisoflavone; 4-(5,7-dihydroxy-4-oxo-4H-chromen-3-yl)phenyl beta-D-glucopyranoside; 5,7-dihydroxy-3-(4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-4H-chromen-4-one; 3-{4-[(2S,4S,5S,3R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydr opyran-2-yloxy)]phenyl}-5,7-d

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5321398
CAS Number: CAS 152-95-4
TTD Drug ID: DM4A0NP

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukin-5 (IL5)	TTPREZD	IL5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Interleukin-5 (IL5)	DTT	IL5	6.51E-01	-0.02	-0.11
Interleukin-5 (IL5)	DTT	IL5	1.71E-04	0.12	0.71

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Design and synthesis of novel hydroxyalkylaminomethylchromones for their IL-5 inhibitory activity. Bioorg Med Chem. 2010 Jul 1;18(13):4625-9.