Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM4UWKR)

Drug Name
PMID18800762C11 Drug Info
Synonyms bisphosphonate, 11; UNII-S888WM4024; S888WM4024; 16610-63-2; Tensan AO; AC1NA3ZJ; GTPL3191; BDBM25285; DB07873
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
4395717
CAS Number
CAS 16610-63-2
TTD Drug ID
DM4UWKR

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Geranyltranstransferase (FDPS) TTIKWV4 FPPS_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Geranyltranstransferase (FDPS) DTT FDPS 7.06E-03 -0.73 -2.57
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. J Med Chem. 2008 Sep 25;51(18):5594-607.