General Information of Drug (ID: DM57ZMJ)

Drug Name
3-(1,1-Dimethyl-2-phenyl-ethyl)-pyridine Drug Info
Synonyms
CHEMBL440299; 87372-78-9; 3-(1,1-Dimethyl-2-phenyl-ethyl)-pyridine; CTK3C4529; DTXSID20658229; ZINC29556563; BDBM50028169; 3-(2-Methyl-1-phenylpropan-2-yl)pyridine; Pyridine, 3-(1,1-dimethyl-2-phenylethyl)-
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44299138
CAS Number
CAS 87372-78-9
TTD Drug ID
DM57ZMJ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Steroid 11-beta-hydroxylase (CYP11B1) TTIQUX7 C11B1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Steroid 11-beta-hydroxylase (CYP11B1) DTT CYP11B1 5.647 4.954 5.678 6.194
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Steroid 11-beta-hydroxylase (CYP11B1) DTT CYP11B1 4.31E-04 -0.03 -0.13
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Structure-activity relationship study of the inhibition of adrenal cortical 11 beta-hydroxylase by new metyrapone analogues. J Med Chem. 1984 Jan;27(1):15-9.