Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM65WZ7)

Drug Name

5-benzhydryl-1,3,4-oxadiazole-2(3H)-thione Drug Info

Synonyms

CHEMBL593832; 5-benzhydryl-1,3,4-oxadiazole-2-thiol; 93073-39-3; 5-(diphenylmethyl)-1,3,4-oxadiazole-2-thiol; AC1MJWI7; 5-benzhydryl-3H-1,3,4-oxadiazole-2-thione; 5-benzhydryl-1,3,4-oxadiazole-2(3H)-thione; MolPort-001-902-005; ZINC17946026; STK803293; BDBM50320727; BBL012648; AKOS002344283; MCULE-6937439472; BAS 00805225; 5-Benzhydryl-[1,3,4]oxadiazole-2-thiol; SR-01000312098; 5-Diphenylmethyl-1,3,4-oxadiazole-2(3H)-thione

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 3119329
TTD Drug ID: DM65WZ7

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosinase (TYR)	TTULVH8	TYRO_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tyrosinase (TYR)	DTT	TYR	5.959	5.711	5.973	4.912

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tyrosinase (TYR)	DTT	TYR	6.68E-04	2.54	1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triaz... Bioorg Med Chem. 2010 Jun 1;18(11):4042-8.