Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM6FNVC)

Drug Name

6-Hydroxyflavanone Drug Info

Synonyms

6-Hydroxyflavanone; 4250-77-5; 6-hydroxy-2-phenylchroman-4-one; 6-hydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one; 6-Hydroxy-Flavanone; CHEMBL195033; 4H-1-Benzopyran-4-one, 2,3-dihydro-6-hydroxy-2-phenyl-; CHEBI:34471; XYHWPQUEOOBIOW-UHFFFAOYSA-N; 6-hydroxy-2-phenyl-chroman-4-one; MFCD00017485; 6-hydroxy-2-phenyl-2,3-dihydrochromen-4-one; Flavanone, 6-hydroxy-; (+/-)-6-Hydroxyflavanone; 6 - Hydroxyflavanone; ACMC-209jpu; AC1MC1GQ; Maybridge3_000570; 6-Hydroxyflavanone, 99%; bmse000985; C14221; Oprea1_761592; SCHEMBL126598

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2734580
ChEBI ID: CHEBI:34471
CAS Number: CAS 4250-77-5
TTD Drug ID: DM6FNVC

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Androgen receptor messenger RNA (AR mRNA)	TTKPW01	ANDR_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Androgen receptor messenger RNA (AR mRNA)	DTT	AR	5.955	4.868	5.902	5.567

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Androgen receptor messenger RNA (AR mRNA)	DTT	AR	4.81E-01	-0.23	-0.29

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4706-10.