Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM6JTNW)

Drug Name

3-(2,5-Dioxo-pyrrolidin-1-yl)-benzoic acid Drug Info

Synonyms

3-(2,5-dioxopyrrolidin-1-yl)benzoic acid; 60693-31-4; 3-(2,5-Dioxo-pyrrolidin-1-yl)-benzoic acid; 3-(2,5-dioxo-1-pyrrolidinyl)benzoic acid; 3-(2,5-dioxoazolidinyl)benzoic acid; AC1LETYJ; BAS 16153444; Enamine_005131; 3-succinimidobenzoic acid; 3-Succinimidylbenzoic acid; Cambridge id 5631823; AC1Q5U3M; AC1Q73IP; Oprea1_343380; Oprea1_386853; MLS000061625; SCHEMBL20053775; ZINC63844; CTK5B2080; DTXSID80351143; MolPort-000-385-168; HMS1408J05; ANW-46498; STK155926; SBB011404; AKOS000112869; MCULE-3726251625; IDI1_007718; SMR000069955

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 692331
CAS Number: CAS 60693-31-4
TTD Drug ID: DM6JTNW

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acetylcholinesterase (AChE)	TT1RS9F	ACES_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Acetylcholinesterase (AChE)	DTT	ACHE	1.678	1.926	1.766	5.252

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Acetylcholinesterase (AChE)	DTT	ACHE	6.39E-02	-1.07	-1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives. Bioorg Med Chem Lett. 2003 May 19;13(10):1825-7.