Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM6PQ5V)

Drug Name

4-amino-N-(2-chlorophenyl)benzenesulfonamide Drug Info

Synonyms

19837-85-5; 4-amino-N-(2-chlorophenyl)benzenesulfonamide; 4-amino-N-(2-chlorophenyl)benzene-1-sulfonamide; 4-Amino-N-(2-chloro-phenyl)-benzenesulfonamide; Benzenesulfonamide, 4-amino-N-(2-chlorophenyl)-; AC1MP5DG; AC1Q51WZ; SCHEMBL1970942; n1-2-chlorophenylsulphanilamide; CHEMBL227597; CTK4E2501; DTXSID20392191; XZQHDUUDKCHQIL-UHFFFAOYSA-N; MolPort-002-463-078; ZINC3885452; STL420385; BBL034801; AKOS000115492; NE25153; MCULE-7275329899; KB-289984; FT-0719132; N-(2-Chlorophenyl)-4-aminobenzenesulfonamide; EN300-02335

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 3405810
CAS Number: CAS 19837-85-5
TTD Drug ID: DM6PQ5V

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin G/H synthase 1 (COX-1)	TT8NGED	PGH1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	6.09	7.747	6.04	7.023

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	3.97E-03	0.16	0.43

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Analgesic agents without gastric damage: design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors. Bioorg Med Chem. 2007 Jan 15;15(2):1014-21.