Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM6XN4C)

Drug Name
CAR-T cells targeting CD22 Drug Info
Indication
Disease Entry ICD 11 Status REF
Non-hodgkin lymphoma 2B33.5 Phase 2 [1]
leukaemia 2A60-2B33 Phase 1/2 [2]
Lymphoma 2A80-2A86 Phase 1/2 [2]
Multiple myeloma 2A83 Phase 1/2 [2]
Cross-matching ID
TTD Drug ID
DM6XN4C

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
B-cell receptor CD22 (CD22) TTM6QSK CD22_HUMAN CAR-T-Cell-Therapy [2]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Non-hodgkin lymphoma
ICD Disease Classification 2B33.5
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
B-cell receptor CD22 (CD22) DTT CD22 1.89E-11 -0.21 -0.58
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT03196830) CAR-T for R/R B-NHL
2 ClinicalTrials.gov (NCT03312205) CAR-T Cells for Relapsed or Refractory Haematopoietic and Lymphoid Malignancies