Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM71BIC)

Drug Name
LOR-220 Drug Info
Synonyms ML-220; PI3K-targeting small molecules (cancer), Lorus; Phosphoinositide-3 kinase-targeting small molecules (cancer), Lorus
Indication
Disease Entry ICD 11 Status REF
Bacterial infection 1A00-1C4Z Investigative [1]
Cross-matching ID
PubChem CID
11851317
TTD Drug ID
DM71BIC

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Bacterial infection
ICD Disease Classification 1A00-1C4Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase gamma (PIK3CG) DTT PIK3CG 1.98E-01 -0.05 -0.55
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2155).