Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM7MUZ1)

Drug Name

2-Hydroxymethyl-Pyrrolidine-3,4-Diol Drug Info

Synonyms

2-(Hydroxymethyl)-[2R-(2a,3b,4b)]-3,4-Pyrrolidinediol; 2-(Hydroxymethyl)-(2R-(2a,3b,4b))-3,4-Pyrrolidinediol; ACMC-20m9e3; ACMC-20m1d3; ACMC-20m9e4; 3,4-Pyrrolidinediol,2-(hydroxymethyl)-, (2S,3S,4R)-; 3,4-Pyrrolidinediol,2-(hydroxymethyl)-, (2R,3R,4S)-; AC1L1B8Z; 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-, (2R,3S,4S)-; SCHEMBL981088; CTK8A3364; 1,4-dideoxy-1,4-iminopentitol; OQEBIHBLFRADNM-UHFFFAOYSA-N; HMS3373I18; IMR; 97058-12-3

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 127716
CAS Number: CAS 100937-53-9
TTD Drug ID: DM7MUZ1

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Purine nucleoside phosphorylase (PNP)	TTMCF1Y	PNPH_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Purine nucleoside phosphorylase (PNP)	DTT	PNP	7.85	7.15	8.34	8.782

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Purine nucleoside phosphorylase (PNP)	DTT	PNP	3.67E-04	1.95	2.55

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.