Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM7SA9J)

Drug Name

IR-103 Drug Info

Synonyms

HIV vaccine + Amplivax, IRC; HIV vaccine + Amplivax, Immune Response Corp; HIV vaccine + HYB-2055, IRC; HIV vaccine + HYB-2055, Immune Response Corp; Vaccine (HIV) + Amplivax, IRC; Vaccine (HIV) + Amplivax, Immune Response Corp; Vaccine (HIV) + HYB-2055, IRC; Vaccine (HIV) + HYB-2055, Immune Response Corp

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus infection	1C62	Discontinued in Phase 3	[1]

Cross-matching ID

TTD Drug ID: DM7SA9J

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Toll-like receptor 9 (TLR9)	TTSHG0T	TLR9_HUMAN	Not Available	[2]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Human immunodeficiency virus infection

ICD Disease Classification

1C62

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Toll-like receptor 9 (TLR9)	DTT	TLR9	2.58E-01	-0.06	-0.17

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019204)
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1759).