Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8B1Q4)

Drug Name
US8889672, 252-036-001 Drug Info
Synonyms SCHEMBL13837647; CHEMBL2393427; BDBM139472; US8889672, 252-036-001
Cross-matching ID
PubChem CID
71009752
ChEBI ID
CHEMBL2393427
TTD Drug ID
DM8B1Q4

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Protein kinase C zeta (PRKCZ) TTUWGRA KPCZ_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Protein kinase C zeta (PRKCZ) DTT PRKCZ 3.935 6.204 5.503 7.245
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Protein kinase C zeta (PRKCZ) DTT PRKCZ 5.78E-42 0.75 0.9
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Compounds, formulations, and methods of protein kinase C inhibition. US8889672.