Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8PYAN)

Drug Name

Ro-40-0655 Drug Info

Synonyms

RAR-alpha agonist, Roche

Indication

Disease Entry	ICD 11	Status	REF
Colorectal cancer	2B91.Z	Investigative	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Retinoic acid receptor alpha (RARA)	TTW38KT	RARA_HUMAN	Agonist	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Retinoic acid receptor alpha (RARA)	DTT	RARA	3.096	4.45	3.892	5.6

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Colorectal cancer

ICD Disease Classification

2B91.Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Retinoic acid receptor alpha (RARA)	DTT	RARA	4.46E-01	-0.04	-0.13

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Tamibarotene. Drugs Today (Barc). 2007 Aug;43(8):563-8.