Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8SINB)

Drug Name
SDZ-LAV-694 Drug Info
Synonyms LAV-694; 6-[2-(2,5-Dimethoxyphenyl)ethyl]-4-ethylquinazoline
Indication
Disease Entry ICD 11 Status REF
Actinic keratosis EK90.0 Phase 1 [1]
Cross-matching ID
PubChem CID
9949064
TTD Drug ID
DM8SINB

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tubulin (TUB) TTML2WA NOUNIPROTAC Inhibitor [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Tubulin (TUB) DTT TUB 7.743 8.411 8.625 8.347
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Actinic keratosis
ICD Disease Classification EK90.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tubulin (TUB) DTT NO-GeName 7.94E-02 0.35 0.43
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Recent patents reveal microtubules as persistent promising target for novel drug development for cancers. Recent Pat Antiinfect Drug Discov. 2009 Nov;4(3):164-82.
2 Recent Patents Reveal Microtubules as Persistent Promising Target for Novel Drug Development for Cancers. Recent Patents on Anti-Infective Drug Discovery 12/2009; 4(3):164-82.