Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM9GFOM)

Drug Name

ProstaRex Drug Info

Synonyms

AIT (prostate cancer), AltaRex; Protate cancer therapy, ViRexx/United Therapeutics; AIT (prostate cancer), ViRexx/United Therapeutics; Anti-idiotype induction therapy (prostate cancer), Paladin; Anti-idiotype induction therapy (prostate cancer), United Therapeutics; Anti-idiotype induction therapy (prostate cancer), AltaRex/United Therapeutics

Indication

Disease Entry	ICD 11	Status	REF
Prostate cancer	2C82.0	Investigative	[1]

Cross-matching ID

TTD Drug ID: DM9GFOM

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostate specific antigen (KLK3)	TTS78AZ	KLK3_HUMAN	Modulator	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostate specific antigen (KLK3)	DTT	KLK3	2.524	3.991	2.248	4.76

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification

02 Neoplasm

Disease Class

ICD-11: 2C82 Prostate cancer

The Studied Tissue

Prostate

The Studied Disease

Prostate cancer [ICD-11:2C82]

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostate specific antigen (KLK3)	DTT	KLK3	2.01E-01	-0.04	-0.09

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2373).