Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM9MFUN)

Drug Name
PMID25726713-Compound-17 Drug Info
Cross-matching ID
TTD Drug ID
DM9MFUN

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Smoothened D473H mutant (SMO D473H) TTW6JVU SMO_HUMAN Antagonist [1]
Smoothened homolog (SMO) TT8J1S3 SMO_HUMAN Antagonist [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Smoothened homolog (SMO) DTT SMO 4.01E-06 -0.18 -0.35
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Hedgehog inhibitors: a patent review (2013 - present).Expert Opin Ther Pat. 2015 May;25(5):549-65.