Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMA6O9R)

Drug Name
SAR-389644 Drug Info
Synonyms SAR-389644C; Prostaglandin D2 antagonist (asthma/allergic rhinitis), sanofi-aventis
Indication
Disease Entry ICD 11 Status REF
Allergic rhinitis CA08.0 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMA6O9R

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin D2 receptor (PTGDR) TTNVEIR PD2R_HUMAN Antagonist [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Prostaglandin D2 receptor (PTGDR) DTT PTGDR 1.609 4.087 1.433 1.963
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Allergic rhinitis
ICD Disease Classification CA08.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Prostaglandin D2 receptor (PTGDR) DTT PTGDR 7.32E-02 -0.05 -0.2
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025865)
2 US patent application no. 2008,0300,217, Combination therapy with fumaric acid esters for the treatment of autoimmune and,or inflammatory disorders.