Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMA7EFM)

Drug Name

Human chorionic gonadotropin Drug Info

Synonyms

Human chorionic gonadotropin (heart disease); HCG (heart disease), Stem Cell Therapeutics; Human chorionic gonadotropin (heart disease), Stem Cell Therapeutics

Indication

Disease Entry	ICD 11	Status	REF
Heart disease	BA41-BA42	Terminated	[1]

Cross-matching ID

TTD Drug ID: DMA7EFM

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Luteinizing hormone receptor (LHCGR)	TT2O4W9	LSHR_HUMAN	Inhibitor	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Luteinizing hormone receptor (LHCGR)	DTT	LHCGR	4.009	2.561	3.365	4.828

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Heart disease

ICD Disease Classification

BA41-BA42

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Luteinizing hormone receptor (LHCGR)	DTT	LHCGR	3.55E-01	5.41E-04	4.54E-03

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1160).
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 254).