Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMA97CS)

Drug Name
(5Z,9Z)-5,9-heptacosadienoic acid Drug Info
Synonyms (5Z,9Z)-5,9-heptacosadienoic acid; 5Z,9Z-heptacosadienoic acid; CHEMBL463437; 27:2(5Z,9Z); LMFA01020363
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44567153
TTD Drug ID
DMA97CS

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA topoisomerase I (TOP1) TTGTQHC TOP1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
DNA topoisomerase I (TOP1) DTT TOP1 6.65E-01 0.2 0.39
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Total synthesis and biological evaluation of (5Z,9Z)-5,9-hexadecadienoic acid, an inhibitor of human topoisomerase I. J Nat Prod. 2002 Nov;65(11):1715-8.