Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMAEHFT)

• Drug Name: O-Acetylserine Drug Info
• Synonyms: O-acetyl-L-serine; O-acetylserine; 5147-00-2; (S)-3-Acetoxy-2-aminopropanoic acid; O3-acetyl-L-serine; O-AC-L-Ser-OH; L-Serine, acetate (ester); acetylserine; Serine, O-acetyl-; Poly-O-acetylserine; (2S)-3-acetoxy-2-ammoniopropanoate; (2S)-3-acetoxy-2-azaniumylpropanoate; Poly-O-acetyl-L-serine; o-acetyl-serine; O-acetyl-l-ser; OAS; NSC 226230; L-Serine, O-acetyl-; bmse000983; AC1L40XB; SCHEMBL598363; AC1Q60A2; CHEBI:17981; CTK1H1469; VZXPDPZARILFQX-BYPYZUCNSA-N; MolPort-001-762-455; ZINC895446; 7170AB; ANW-60944; FCH833665

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 99478
  ChEBI ID: CHEBI:17981
  CAS Number: CAS 5147-00-2
  TTD Drug ID: DMAEHFT

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin G/H synthase 1 (COX-1)	TT8NGED	PGH1_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	6.09	7.747	6.04	7.023

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	3.97E-03	0.16	0.43

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.