Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMAEWHB)

Drug Name

1-Deoxy-1-Thio-Heptaethylene Glycol Drug Info

Synonyms

1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL; PE7; 20-sulfanyl-3,6,9,12,15,18-hexaoxaicosan-1-ol; AC1L9JR2; MolPort-006-168-364; ZINC5828797; DB02404; 3,6,9,12,15,18-Hexaoxa-20-mercaptoicosane-1-ol

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 446506
TTD Drug ID: DMAEWHB

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acetylcholinesterase (AChE)	TT1RS9F	ACES_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Acetylcholinesterase (AChE)	DTT	ACHE	1.678	1.926	1.766	5.252

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Acetylcholinesterase (AChE)	DTT	ACHE	6.39E-02	-1.07	-1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.