Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMBR7O0)

Drug Name

SALVINORIN B Drug Info

Synonyms

Salvinorin B; CHEMBL424698; 92545-30-7; Divinorin B; (-)-Salvinorin B; SCHEMBL3144611; DTXSID50465988; BLTMVAIOAAGYAR-CEFSSPBYSA-N; (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-Furanyl)dodecahydro-9-hydroxy-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic Acid Methyl Ester; ZINC15449154; BDBM50189136; Salvinorin B, > =93.0% (HPLC); AKOS027326793; NCGC00181787-01; Salvinorin B solution, 1.0 mg/mL in acetonitrile: water (9:1), ampule of 1 mL, certified reference material; [2S-(2; A,4a; A,6a; A,9; A,10a; A,10b

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 11440685
CAS Number: CAS 92545-30-7
TTD Drug ID: DMBR7O0

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Opioid receptor kappa (OPRK1)	TTQW87Y	OPRK_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Opioid receptor kappa (OPRK1)	DTT	OPRK1	5.533	5.372	5.703	5.632

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Opioid receptor kappa (OPRK1)	DTT	OPRK1	9.17E-01	0.04	0.1

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Herkinorin analogues with differential beta-arrestin-2 interactions. J Med Chem. 2008 Apr 24;51(8):2421-31.