Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMBZJT5)

Drug Name

(3-((1H-imidazol-1-yl)methyl)phenyl)methanol Drug Info

Synonyms

[3-(1H-Imidazol-1-ylmethyl)phenyl]methanol; 151055-79-7; CHEMBL597368; W-205714; [3-(imidazol-1-ylmethyl)phenyl]methanol; Benzenemethanol, 3-(1H-imidazol-1-ylmethyl)-; (3-((1H-imidazol-1-yl)methyl)phenyl)methanol; SCHEMBL3092795; DTXSID60439216; MolPort-000-143-255; ZX-AT016572; BDBM50307217; ZINC12370274; SBB090815; FCH921386; AKOS006343964; RP03595; [3-(imidazolylmethyl)phenyl]methan-1-ol; DB-063877; FT-0703495; Y7599; Benzenemethanol,3-(1H-imidazol-1-ylmethyl)-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 10397593
CAS Number: CAS 151055-79-7
TTD Drug ID: DMBZJT5

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Steroid 11-beta-hydroxylase (CYP11B1)	TTIQUX7	C11B1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Steroid 11-beta-hydroxylase (CYP11B1)	DTT	CYP11B1	5.647	4.954	5.678	6.194

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Steroid 11-beta-hydroxylase (CYP11B1)	DTT	CYP11B1	4.31E-04	-0.03	-0.13

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25.