Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMCH7GO)

Drug Name

N1-(4-bromophenyl)-N2,N2-dipentylphthalamide Drug Info

Synonyms

CHEMBL523749; N'-(4-bromophenyl)-N,N-dipentylbenzene-1,2-dicarboxamide; AC1MDHAQ; N1-(4-bromophenyl)-N2,N2-dipentylphthalamide; MolPort-002-139-379; ZINC9510931; BDBM50265685; STK055903; AKOS005386817; MCULE-4023922974

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2836828
TTD Drug ID: DMCH7GO

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cannabinoid receptor 2 (CB2)	TTMSFAW	CNR2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Cannabinoid receptor 2 (CB2)	DTT	CNR2	7.037	6.733	6.944	7.163

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Cannabinoid receptor 2 (CB2)	DTT	CNR2	3.82E-02	-0.43	-1.18

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow. J Med Chem. 2009 Jan 22;52(2):369-78.