Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DME6UOM)

Drug Name

4-Methyl-pyridine Drug Info

Synonyms

4-METHYLPYRIDINE; 4-Picoline; 108-89-4; Pyridine, 4-methyl-; p-Picoline; gamma-Picoline; p-Methylpyridine; 4-methyl-pyridine; gamma-Methylpyridine; Ba 35846; UNII-TJD6V9SSO7; .gamma.-Picoline; NSC 18252; 4-Mepy; CCRIS 1723; .gamma.-Methylpyridine; HSDB 5386; EINECS 203-626-4; TJD6V9SSO7; AI3-24111; CHEBI:32547; FKNQCJSGGFJEIZ-UHFFFAOYSA-N; 4-Picoline, 99%; DSSTox_CID_1892; DSSTox_RID_76389; DSSTox_GSID_21892; 4-methyl pyridine; CAS-108-89-4; gamma-picolin; 4-Pyridylmethyl; 4-pi-coline; para-Methylpyridine; Methyl, 4-pyridinyl-; 4-Picoline

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 7963
ChEBI ID: CHEBI:32547
CAS Number: CAS 108-89-4
TTD Drug ID: DME6UOM

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Thromboxane-A synthase (TBXAS1)	TTKNWZ4	THAS_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Thromboxane-A synthase (TBXAS1)	DTT	TBXAS1	5.289	4.615	4.413	3.585

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Thromboxane-A synthase (TBXAS1)	DTT	TBXAS1	6.56E-01	0.02	0.08

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives. J Med Chem. 1981 Oct;24(10):1149-55.