Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFG2S5)

Drug Name

2-(2-chlorophenyl)-2-morpholinoethanamine Drug Info

Synonyms

866782-01-6; 2-(2-Chlorophenyl)-2-morpholin-4-ylethylamine; 2-(2-chlorophenyl)-2-(morpholin-4-yl)ethan-1-amine; 2-(2-chlorophenyl)-2-morpholinoethanamine; CHEMBL382382; 4-Morpholineethanamine,b-(2-chlorophenyl)-; 2-(2-chlorophenyl)-2-morpholin-4-ylethanamine; 2-(2-Chlorophenyl)-2-morpholinoethylamine; 2-(2-Chlorophenyl)-2-(morpholin-4-yl)ethylamine; beta-phenethylamine 6; AC1MZFUY; AC1Q53NI; SCHEMBL8276869; CTK5F7083; BDBM11556; DCA-S02-0; DTXSID90397254; MolPort-001-760-150; KS-000029ZH; 4759AH; SBB073200; AR3509

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 3847395
CAS Number: CAS 866782-01-6
TTD Drug ID: DMFG2S5

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Dipeptidyl peptidase 4 (DPP-4)	TTDIGC1	DPP4_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Dipeptidyl peptidase 4 (DPP-4)	DTT	DPP4	4.995	4.926	7.852	8.358

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Dipeptidyl peptidase 4 (DPP-4)	DTT	DPP4	9.54E-01	-0.27	-1.85

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	In silico fragment-based discovery of DPP-IV S1 pocket binders. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1405-9.