Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFLUTR)

Drug Name
Glucagon recombinant Drug Info
Synonyms Glucagon recombinant; GTPL1136; CHEMBL266481
Indication
Disease Entry ICD 11 Status REF
Hypoglycemia 5A41 Approved [1]
Short bowel syndrome KB89.1 Approved [2]
Therapeutic Class
Antihypoglycemic Agents
Cross-matching ID
PubChem CID
44278361
ChEBI ID
CHEMBL5391
TTD Drug ID
DMFLUTR

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucagon receptor (GCGR) TT9O6WS GLR_HUMAN Binder [3]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Glucagon receptor (GCGR) DTT GCGR 4.695 1.926 1.322 3.797
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Hypoglycemia
ICD Disease Classification 5A41
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glucagon receptor (GCGR) DTT GCGR 7.24E-02 -0.52 -0.92
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2 Where are we at with short bowel syndrome and small bowel transplant. World J Transplant. 2012 Dec 24;2(6):95-103.
3 Glucagon receptor expression and glucagon stimulation of ghrelin secretion in rat stomach. Biochem Biophys Res Commun. 2007 Jun 15;357(4):865-70.