Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMG2SQM)

Drug Name
SYN-1134 Drug Info
Synonyms Elastase inhibitors, NAEJA; SYN-1360; SYN-1386; SYN-1389; SYN-1390; SYN-1396
Indication
Disease Entry ICD 11 Status REF
Cystic fibrosis CA25 Terminated [1]
Cross-matching ID
TTD Drug ID
DMG2SQM

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pancreatic elastase 1 (CELA1) TT3NKIB CELA1_HUMAN Inhibitor [2]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Cystic fibrosis
ICD Disease Classification CA25
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Pancreatic elastase 1 (CELA1) DTT CELA1 8.56E-02 0.06 0.25
Pancreatic elastase 1 (CELA1) DTT CELA1 3.82E-02 0.19 0.7
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018646)
2 EP patent application no. 1292314, Method for treating respiratory disorders associated with pulmonary elastic fiber injury comprising the use of glycosaminoglycans.