Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMGIN7J)

Drug Name
Onyvax-105 Drug Info
Synonyms Antibody therapy (colerectal cancer), CRC/Onyvax; Vaccine (colorectal cancer), CRC/ImClone; Vaccine (colorectal cancer), CRC/Onyvax
Indication
Disease Entry ICD 11 Status REF
Prostate cancer 2C82.0 Phase 1/2 [1]
Colorectal cancer 2B91.Z Discontinued in Phase 1 [2]
Cross-matching ID
TTD Drug ID
DMGIN7J

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement decay-accelerating factor (CD55) TT5Z9WY DAF_HUMAN Not Available [3]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Complement decay-accelerating factor (CD55) DTT CD55 6.754 6.394 5.638 7.012
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Prostate cancer
ICD Disease Classification 2C82.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement decay-accelerating factor (CD55) DTT CD55 2.44E-02 2.16 3.38
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Onyvax-105 Cancer Vaccine Shows Encouraging Clinical Results in Osteosarcoma Patients After Intensive Chemotherapy. Onyvax vaccines therapies. April 19, 2005.
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006889)
3 Technology evaluation: Onyvax-105, Onyvax. Curr Opin Mol Ther. 2003 Dec;5(6):668-72.